Background
In the field of mechanical circulatory support, there are three types of preclinical evaluation:
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In silico testing is the computer modelling of a system allowing a rapid, risk free and non-invasive development of a product.
In vitro evaluation is achieved using environments similar to those of a human. For example, mock circulation loops can be used to represent the human circulatory system.
In vivo is the final stage of preclinical evaluation where animals are used to test prototypes.